Biochemistry 2280A Lecture Notes - Lecture 24: Benign Tumor, Basal Lamina, Xeroderma Pigmentosum
20 Feb 2017
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Document Summary
The leading cause of death in north america. A disease characterized by the rapid proliferation of an abnormal cell derived from one of. Is becoming more prevalent as the population ages the organisms own cells. Proliferate in defiance of the normal constraints. Invade and colonize territories normally reserved for other cells. Cancer is characterization by genetic and biochemical defects. Biochemistry and molecular biology provide avenues for cures. Benign tumours are contained within the originating tissue: encapsulated, cells do not spread, cells proliferate excessively but remain clustered together in a single mass, forming a tumour. Cells grow as a benign tumour in epithelium. Adhere to blood vessel wall in liver. Different cancers tend to spread to different sites. Common sites of spread are to the bone, liver and lungs. Susceptibility to cancer can be inherited: retinoblastoma (cancer of the eye, xeroderma pigmentosa (cancer of the skin, some forms of breast, prostate, ovarian and intestinal cancers.
