Biochemistry 2280A Lecture Notes - Lecture 13: Anomer, Glycosidic Bond, London Dispersion Force

• School: Western University
• Department: Biochemistry
• Course: Biochemistry 2280A
• Professor: Unknown

Document Summary

Dna is genetic makeup providing instructions that can be read. Rna: multiple functions to do with transcription and translation of dna, mrna: what get when transcribe a gene, protein made from ribosomes: composed of rrna, trna: brings amino acids, splicing-snrnas, microrrn-regulation in mrna, telomere maintenance. Name for the entire nucleoside (base + sugar) = cytidine. Base + sugar + at least one phosphate like atp but has cytosine instead of adenine. Deoxyribonucleotide: sa(cid:373)e as a (cid:374)u(cid:272)leotide e(cid:454)(cid:272)ept o(cid:374) the (cid:1006)" (cid:272)ar(cid:271)o(cid:374) has a h i(cid:374)stead of oh. Uracil identical to thymine except it lacks a methyl group. Planar-flat single ringed puri(cid:374)es a(cid:374)d p(cid:455)r(cid:373)adi(cid:374)es are joi(cid:374)ed to the a(cid:374)o(cid:373)eri(cid:272) (cid:894)(cid:1005)"(cid:895) (cid:272)ar(cid:271)o(cid:374) of ri(cid:271)ose or deo(cid:454)(cid:455)ri(cid:271)ose via n- glycosidic bond. Anomeric carbon ordinarily in the b configuration when joined to nitrogenous base polynucleotides/oligonucleotides: Nucleotides joi(cid:374)ed fro(cid:373) (cid:1007)" (cid:272)ar(cid:271)o(cid:374) to 5" (cid:272)ar(cid:271)o(cid:374) Anytime have a nucleic acid sequence with no specification, assume that it starts with the 5" e(cid:374)d.