Biochemistry 2280A Lecture Notes - Lecture 13: Diabetes Mellitus Type 1, Diabetes Mellitus Type 2, Triglyceride

• School: Western University
• Department: Biochemistry
• Course: Biochemistry 2280A
• Professor: Bonnie Mac Lachlan

Document Summary

Unit 2: energy metabolism lesson 13: energy metabolism summary (oct. 26th 2017) Fed state: high blood glucose, all the following processes are turned on; the reverse will be shut down. Low blood glucose: glycogen use is very rapid, first defense, can be used for up to a day at most. Low blood glucose: glycogen breakdown comes first, happens very regularly (at night), gluconeogenesis uses amino acids from muscle cells to make glucose, predominates when glycogen storage runs out. Looking to make atp through all energy pathways: fatty acids are then going to be broken down into acetyl-coa, takes fatty acids from the blood stream (other than in brain), ketone bodies are produced as well. Healthy response to high blood glucose: high blood glucose pancreas secretes insulin. Insulin prevents breakdown of triacylglycerol, promotes the use of glucose: glucose is stored in the glycogen molecules, this reduces the (cid:271)lood sugar, do(cid:374)"t (cid:449)a(cid:374)t (cid:271)lood glu(cid:272)ose too high.