Biochemistry 2280A Lecture Notes - Lecture 21: Oxidative Phosphorylation, Lipid Bilayer, Electrochemical Gradient

• School: Western University
• Department: Biochemistry
• Course: Biochemistry 2280A
• Professor: Derek Mc Lachlin

Document Summary

Note: qh2 is hydrophobic and is actually inside the membrane (lipid bilayer) in reality. The electron transport chain forms a proton gradient across the inner mitochondrial membrane, which drives the synthesis of atp via chemiosmosis. All of the following electron carriers are cofactors; some sort of non-protein molecule that associates with a protein to help it do its job. In the electron transport chain, electrons pass from one carrier to the next in a strictly defined order outlined below: nicotinamide (nad, connected to amino acid, each nicotinamide accepts 2 electrons, nad(p)+ nad(p)h. Note: nadh made in the cytosol during glycolysis can give its electrons to the electron transport chain in the matrix through a malate-aspartate shuttle. 2 nad+ + 2 h2o + 20 h+ intermembrane space. Complex ii: complex ii is not part of the etc, complex ii is involved in the citric acid cycle.