Biochemistry 2280A Lecture Notes - Lecture 4: Protein Domain, Enzyme Kinetics, Substituent

• School: Western University
• Department: Biochemistry
• Course: Biochemistry 2280A
• Professor: Brian Dempsey

Document Summary

Lecture notes: some common characteristics allow many proteins to function, e. g. protein flexibility, proteins that are not rigid can undergo modest changes in structure called. In the case of enzymes, this area is termed the substrate-binding site or just. Active site : thus, a protein might recognize just 1 or 2 out of thousands of other molecules in the cell, a ligand is a substance that forms a complex with a biomolecule to serve a biological purpose. In protein-ligand binding, the ligand is usually a molecule which produces a signal by binding to a site on a target protein. Explain the concept of dissociation constant (k: ligand binding is characterized by a dissociation constant, k, whose value is calculated from the affinity of the molecules for each other. Describe the structure and function of myoglobin, hemoglobin, and collagen in terms of the 4 attributes of protein structure.