Biochemistry 2280A Lecture Notes - Human Serum Albumin, Posterior Pituitary, Thyrotropin Receptor

• School: Western University
• Department: Biochemistry
• Course: Biochemistry 2280A
• Professor: Tom Stavraky

Document Summary

Endocrinology: describe the functional anatomy of the hypothalamic-pituitary unit hypothalamus surrounds or lines the 3rd ventricle of the brain immediately superior to the pituitary. Connected to the pituitary by a narrow stalk of unmyelinated axons and network of blood vessels. Neurohypophysis (posterior pituitary) and adenohypophysis (anterior pituitary): name the types of hypothalamic neurons and their functions. Magnocellular neurons terminate in posterior pituitary and secrte vasopressin and oxytocin, parvicellular secrete release/inhibiting hypophyseal factors into portal system such as trh, Crh, ghrh, gnrh, hypothalamic projection neuron synapses with neuronal targets: describe the terms circadian, diurnal, ultradian. Episodic secretion in rhythms that are: circadian is around 24 hours, diurnal is exactly 24 hours and ultradian is minutes of hours: discuss the generation and importance of episodic endocrine secretion. Secreted in bursts: outline the 5 hypothalamic-anterior pituitary axes and 2 posterior pituitary axes. Acth is derived from pomc (also makes - Subunit is common to fsh and lh, heavily glycosylated.