Biochemistry 2288A Lecture Notes - Lecture 17: Glycerol, Pentose, Adipocyte

• School: Western University
• Department: Biochemistry
• Course: Biochemistry 2288A
• Professor: Chris Brandl

Document Summary

Initially, ux through glycolysis and citric acid cycle is high because of high. Eventually, [atp] and other energy indicators increase, inhibiting glycolysis and citric acid cycle. Glycogen synthesis, fatty acid synthesis, pentose phosphate pathway, and biosynthesis are favoured. The dashed lines indicate that initially this happens at a high rate and then slows down. Glucose is produced from glycogen and then gluconeogenesis (from. Adipocytes release fatty acids from storage, and eventually, liver produces ketone bodies (not the main source of energy) Release of fatty acids and glycerol from triglycerols continues, and the sustained level of fatty acid in the blood leads to increase ketone body production in the liver. Glycerol is the main substrate for gluconeogenesis, and oxidation of fatty acids provides the required nadh. Overall, metabolism slows as the body tries to conserve energy. Body is forced to consume protein to provide energy for the brain. https://uwoca-my. sharepoint. com/personal/akalluma_uwo_ca/_layouts/15/wopiframe. aspx?sourcedoc={5e62ed6a-49ad-486b-a23a-ea4b3ec5cbfc}& l