Biochemistry 2288A Lecture Notes - Lecture 11: Microsoft Onenote, Metabolic Pathway, Phosphatase

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Combined sum of the chemical reactions that occur in living organisms. Provide energy and reducing power to the cell. Molecules ow through each metabolic pathway at some rate, called the. Cells must be able to change the ux of molecules through each pathway. Altering enzymatic activity; usually several different enzymes that contribute to control the overall ux. Some reactions with g near zero (at or near equilibrium) under physiological conditions. Relatively small change in substrate concentrations can change the net ow of substrates. Normal uctuations in metabolite concentrations do not make the reverse reaction occur to any substantial degree. Cellular ratio of reactant to product is much higher drive metabolic pathways forward. Optimal points to control the ux through a metabolic pathway. The rst reaction in a metabolic pathway or after a branch point is irreversible. The enzyme that catalyzes this is a target for metabolic control. Ways to control the rate of a reaction.

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