Biochemistry 3386B Lecture Notes - Lecture 1: Therapeutic Drug Monitoring, Phenylalanine Hydroxylase, Prostate Cancer
15 May 2019
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Clinical biochem lecture 1 intro and function of a clinical biochem lab. In ontario, most health care costs are covered by the ministry of health under ohip testing quality: also provides regulatory aspects for lab licensing, inspection and monitoring of, approx. 800 mil diagnostic tests are done half are in laboratory medicine: one hospital biochemistry laboratory can provide about 200 different tests and produce 2. In canada, the costs in laboratory medicine are about bn annually million results a year. Diagnosis of a disease: e. g. , diabetes mellitus test: serum glucose, 2. Screening for a disease: e. g. , screen for pku (phenylketonuria) in newborns for deficiency of phenylalanine hydroxylase, 3. Determine severity of an illness: e. g. serum k needed for nerve transmission in heart & for muscle contraction, normal range 3. 5-5. 0 mmol/l, critical levels 6. 0 mmol/l (may imply a lifethreatening condition, 4.
