Biology 1002B Lecture Notes - Lecture 5: Cystic Fibrosis, Atp-Binding Cassette Transporter, Semipermeable Membrane
8 Feb 2013
School
Department
Course
Professor
Document Summary
Lecture 5: membrane structure and transport: fatty acid. Saturated: tightly linearly packed together (can"t put anymore hydrogens) Unsaturated: double bonds introduces bend/kinks, more fluid. Hydrogenation: when hydrogen is added to a carbon-carbon double bond, membrane permeability. Fatty acid tails give a hydrophobic area. Small nonpolar moelcules: o2, co2 and n2: diffuses through membrane down a concentration gradient. Small and uncharged polar molecules: water and indole. Small and uncharged molecules are the easiest to get through membrane: proteins transport glucose and big or charged molecules (ions, simple diffusion, facilitated diffusion, active transport and abc transporter. Simple diffusion: oxygen diffusion driven by free energy change. Facilitated diffusion: molecule specific channel where potassium and others can leak from high to low concentration. Active transport: one of the many type of abc transporters in the body, go against concentration gradient, endergonic process requires energy, basic structure of abc transporter.
