Biology 1002B Lecture Notes - Lecture 9: Pyruvate Dehydrogenase Complex, Inner Mitochondrial Membrane, Atp Synthase

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8 Feb 2017

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Location, products, distribution in nature and purpose of pathways such as glycolysis, ca cycle, respiratory electron transport etc. Pyruvate oxidation - citric acid cycle: in the matrix. Electron transport and oxidative phosphorylation: inner mitochondrial membrane. Relative potential energy of various intermediate compounds (eg. glucose vs. pyruvate vs. co2) The products are 2 molecules of pyruvate (3 c each) which have less free energy than glycolysis. Phosphoenolpyruvate is converted to pyruvate where it loses a phosphate to create atp. This is substrate level phosphorylation (no oxygen is required). You don"t get much atp but you get enough. Pyruvate oxidation occurs to go from pyruvate (in the cytosol) to go into the matrix. In eukaryotes it occurs in the matrix, and aerobic respiration in bacteria (don"t have mitochondria) occurs in the cytosol as well. Co2 is dumped from the pyruvate because there is no free energy left in there decarboxylation. The transition is called the pyruvate dehydrogenase complex.

Related Questions

Which of the following accurately describe difference(s) between oxidative phosphorylation and substrate-level phosphorylation during aerobic respiration in eukaryotes?

	a.	Oxidative phosphorylation relies on energy initially derived from redox reactions to power ATP synthase, and substrate-level phosphorylation relies on enzymatic reactions to phosphorylate ADP.
	b.	Oxidative phosphorylation takes place in the inner mitochondrial membrane and substrate-level phosphorylation only occurs in the cytosol.
	c.	Oxidative phosphorylation uses oxygen as a substrate and substrate-level phosphorylation uses phosphate.
	d.	Oxidative phosphorylation takes place during glycolysis and the electron transport chain and substrate-level phosphorylation occurs during the citric acid cycle and chemiosmosis.
	e.	Oxidative phosphorylation produces less ATP than substrate-level phosphorylation.

QUESTION 1

Which of the following is the correct order of the three stages of cellular respiration?

	a.	Krebs cycle, glycolysis, electron transport
	b.	electron transport, glycolysis, Krebs cycle
	c.	Krebs cycle, electron transport, glycolysis
	d.	glycolysis, Krebs cycle, electron transport
	e.	electron transport, Krebs cycle, glycolysis

1 points

QUESTION 2

Consider a bacterial cell that performs anaerobic respiration. If that bacterial cell had access to six molecules of glucose to use, how many ATP molecules would it be able to produce?

	a.	2
	b.	34
	c.	36
	d.	6
	e.	12

1 points

QUESTION 3

The oxygen that organisms need to live is used exclusively in which of the following metabolic pathways?

	a.	Electron transport chain
	b.	Anaerobic respiration
	c.	Glycolysis
	d.	Krebs cycle
	e.	ATP-Synthase

1 points

QUESTION 4

The electron transport chain uses the energy in NADH and FADH₂ to pump H⁺ ions from the matrix to the innermembrane space. The H⁺ gradient is then used to power ATP-Synthase. Enough H⁺ is pumped from the energy in a molecule of NADH to produce ______ ATP molecules, while enough H⁺ is pumped from the energy in a FADH₂ molecule to produce ______ ATP molecules.

	a.	three; two
	b.	three; three
	c.	two; two
	d.	two; three

1 points

QUESTION 5

Which of the following list contains only products of cellular respiration?

	a.	glucose, oxygen, ADP
	b.	ATP, carbon dioxide
	c.	oxygen, ADP, carbon dioxide
	d.	ATP, glucose, oxygen
	e.	glucose, ATP

1 points

QUESTION 6

What powers the enzyme ATP-Synthase?

	a.	NADH molecules
	b.	oxygen (O₂)
	c.	ATP
	d.	NADH and FADH₂ molecules
	e.	The H⁺ gradient between the matrix and inner-membrane space

1 points

QUESTION 7

Organisms exist which are able to survive using only glycolysis (i.e. without using oxidative phosphorylation).

True

False

1 points

QUESTION 8

Each ADP molecule contains ________ phosphates, and each ATP molecule contains ________ phosphates.

	a.	three; three
	b.	two; two
	c.	one; two
	d.	two; three
	e.	one; three

1 points

QUESTION 9

Adding a phosphate group to ADP to form ATP is an endergonic reaction.

True

False

1 points

QUESTION 10

The majority of ATP produced during cellular respiration is produced during glycolysis.

True

False

1 points

QUESTION 11

Glycolysis occurs:

	a.	on enzymes located in the inner-membrane.
	b.	in the cytosol.
	c.	in the inner-membrane space.
	d.	in the nucleus of the cell.
	e.	in the matrix of mitochondria.

1 points

QUESTION 12

Muscle soreness associated with strenuous exercise is due to:

	a.	the production of alcohol during anaerobic respiration.
	b.	a buildup of lactic acid.
	c.	an excessive amount of ATP that builds up during exercise.
	d.	the large amounts of CO₂ building up in the muscle.

1 points

QUESTION 13

A required reactant for glycolysis is:

	a.	the electron transport chain.
	b.	carbon dioxide.
	c.	oxygen.
	d.	NAD+.
	e.	mitochondria.

1 points

QUESTION 14

NADH is produced in all of the following except:

	a.	the electron transport chain.
	b.	the Krebs cycle.
	c.	glycolysis.

Question 1 Organisms exist which are able to survive using only glycolysis (i.e. without using oxidative phosphorylation).
True
False

Question 2 Glycolysis occurs:
a. in the matrix of mitochondria.
b. in the inner-membrane space.
c. in the cytosol.
d. in the nucleus of the cell.
e. on enzymes located in the inner-membrane.

Question 3 Muscle soreness associated with strenuous exercise is due to:
a. the large amounts of CO2 building up in the muscle.
b. an excessive amount of ATP that builds up during exercise.
c. a buildup of lactic acid.
d. the production of alcohol during anaerobic respiration.

Question 4 Each ADP molecule contains ________ phosphates, and each ATP molecule contains ________ phosphates.
a. two; three
b. two; two
c. three; three
d. one; three
e. one; two

Question 5 The oxygen that organisms need to live is used exclusively in which of the following metabolic pathways?
a. Glycolysis
b. Electron transport chain
c. Krebs cycle
d. Anaerobic respiration
e. ATP-Synthase

Question 6 NADH is produced in all of the following except:
a. the electron transport chain.
b. glycolysis.
c. the Krebs cycle.

Question 7 Consider a bacterial cell that performs anaerobic respiration. If that bacterial cell had access to six molecules of glucose to use, how many ATP molecules would it be able to produce?
a. 36
b. 6
c. 12
d. 34
e. 2

Question 8 The majority of ATP produced during cellular respiration is produced during glycolysis.
True
False

Question 9 What powers the enzyme ATP-Synthase?
a. The H+ gradient between the matrix and inner-membrane space
b. ATP
c. oxygen (O2)
d. NADH molecules
e. NADH and FADH2 molecules

Question 10 Which of the following list contains only products of cellular respiration?
a. ATP, glucose, oxygen
b. ATP, carbon dioxide
c. oxygen, ADP, carbon dioxide
d. glucose, ATP
e. glucose, oxygen, ADP

Question 11 Adding a phosphate group to ADP to form ATP is an endergonic reaction. True False

Question 12 The electron transport chain uses the energy in NADH and FADH2 to pump H+ ions from the matrix to the innermembrane space. The H+ gradient is then used to power ATP-Synthase. Enough H+ is pumped from the energy in a molecule of NADH to produce ______ ATP molecules, while enough H+ is pumped from the energy in a FADH2 molecule to produce ______ ATP molecules.
a. two; three
b. three; three
c. three; two
d. two; two

Question 13 Which of the following is the correct order of the three stages of cellular respiration?
a. glycolysis, Krebs cycle, electron transport
b. Krebs cycle, electron transport, glycolysis
c. electron transport, Krebs cycle, glycolysis
d. electron transport, glycolysis, Krebs cycle
e. Krebs cycle, glycolysis, electron transport

Question 14 A required reactant for glycolysis is:
a. carbon dioxide.
b. mitochondria.
c. NAD+.
d. the electron transport chain.
e. oxygen.

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Biology 1002B Lecture Notes - Lecture 9: Pyruvate Dehydrogenase Complex, Inner Mitochondrial Membrane, Atp Synthase

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