Biology 1002B Lecture Notes - Lecture 15: Cytosol, Alternative Splicing, Spliceosome

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E. coli don"t interact with lactose on a regular basis. Operon respond to galactoside (not lactose) Laca transacetylase (puts acetyl groups onto molecules: has no function with lactose. Vvaucheria is a coenocytic alga: eukaryotic cell, tube full or organelles. Gene structure is more complicated than in organelles. Promoters: position dependent (have to be in the right place, attract protein transcription factors. Protein coding genes: within promoter is tata box. Polymerase i & iii: transcribes non-protein-coding genes. Always required to transcribe a gene above a basal rate. Help the transcription apparatus to assemble (including rna polymerase) Example: tfiid which contains that sequence that recognizes a tata box helps rna polymerase bind. Could be anywhere on chromosome (do not have to be close promoter) Proximal control elements: located close to promoters help with transcription. Distal control elements: groups of which are called enhancers may be far away from a gene or even in an intron.

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