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Biomembranes.doc

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Department
Biology
Course
Biology 2382B
Professor
Sashko Damjanovski
Semester
Winter

Description
Biomembranes - define a cell Components of Biomembranes - lipids - sterols - proteins Amphipathicity: phospholipids spontaneously form lipid bilayers Fatty Acid - long hydrocarbon chain attached to a polar head group - amphipathic - No double bonds = Saturated - One double bond = unsaturated - More than one double bond = polyunsaturated Effect of double bond on structure of fatty acid  Temperature increases with chain length, decreases with unsaturation (37 degrees)  Cis bonds = common  Trans bonds = rare  Melting point increases with increasing chain length but decreases with increasing unsaturation Types of Lipids Phospholipid = head group attached via phosphate - Phosphoglyceride = derived from 3 carbon glycerol and 3-phosphate scaffold to which the polar head group and 2 acyl chains are attached Common Head groups  PE: phosphatidylethanolamine  PC: phosphatidylcholine  PS: phosphatidylserine  PI: phosphatidylinositol - Sphingomyelin = phospholipid Sphingolipids = derived from sphingosine (amino alcohol) Common sphingolipids SM: sphingomyelin (phospholipid) GlcCer: glucosylceramide (glycolipid) Sphingomyelin = phosp
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