Biology 2382B Lecture Notes - Lecture 10: Aneuploidy, Wee1, Telophase

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29 Jan 2018

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Essential mechanism by which all living things reproduce and pass on genetic information to next generation of cells. Ensures that dna in each chromosome is faithfully replicated to produce 2 copies (somatic cells: i. e. need to replicate the dna perfectly. Replicated chromosomes must be accurately distributed (segregated) to 2 genetically identical daughter cells: after dna replication, the dna must be segregated perfectly (1/2 to each daughter cell) Coordination of growth (increase in cell mass) with division: i. e. make sure the cell is big enough to be divided into two. When observing cell going through the cell cycle, you can"t see much except for during the mitosis phase (m) I. e. we cannot see a cell going through g1/s/g2. Our cells spend the most time in interphase. Duration of this phase depends on the type of cell: e. g. skin cells divide a lot short interphase; liver cells divide very little long interphase.

Related Questions

Part A:

In prokaryotes and eukaryotes cell reproduction is similar in that it requires some kind of signal to proceed, DNA replication, careful separation of the DNA into two equal portions, and division of the cytoplasm. How is cell reproduction different in prokaryotes and eukaryotes?

Select one:

a. In a eukaryotic organism, the signals for cell division are usually not related to the environment but to the function of the entire organism.

b. Eukaryotic cells constantly divide whenever environmental conditions are adequate and the cells are large enough.

c. The linear chromosomes in prokaryotes are constantly being updated.

d. Prokaryotic cell division requires cytokinesis before mitosis because of their small size.

e. The sexual phase of most prokaryotes (bacteria) is essential to the rapid cell division required for infection.

Part B:

What does the name Cyclin Dependent Kinase stand for?

Select one:

a. A protein important to the cell cycle that is dependent on DNA synthesis.

b. An enzyme that cuts DNA so that chromosomes can segregate.

c. An enzyme that phosphorylates other proteins using ATP only when the protein Cyclin is bound to the enzyme.

d. An enzyme that rolls along microtubules dragging a vesicle.

e. An enzyme that connects chromosomes to the spindle fiber.

Part C:

The Cell Cycle is divided into Mitosis, Cytokinesis, and Interphase. Mitosis can be ordered into the following phases:

Select one:

a. Prophase/Prometaphase/Metaphase/Anaphase/Telophase

b. Anaphase/Prometaphase/Metaphase/Prophase/Telophase

c. Metaphase/Anaphase/Telophase/Prophase/Prometaphase

d. Telophase/Prophase/Prometaphase/Metaphase/Anaphase

e. Anaphase/Telophase/Prophase/Prometaphase/Metaphase

Part D:

The Cell Cycle is divided into Mitosis, Cytokinesis, and Interphase. Interphase can be ordered into the following phases:

Select one:

a. S/G1/G2

b. G2/G1/S

c. G1/S/G2

d. G2/S/G1

e. G1/G2/S

amethystyak657

Question 11 options:

A condition characterized by the growth of endometrial cells in areas other than the endometrium is called

Question 12

A standard screening test for cervical cancer is called

Question 13

The period of prenatal development in which the basic parts of the organ systems are formed is the

Question 14 options:

Detection of

Spell check is used by pregnancy test kits to detect the early stages of pregnancy.

Question 15

The actual gene sequence governing the expression of a trait is called a

Spell check , whereas the physical expression of this trait is the PHENOTYPE , which can also be defined as the physical expression of a gene.

Question 16

Down syndrome is a disorder where a person has an chromosome 21.

Question

A picture of all chromosomes taken in metaphase and used for analysis is called a

Question 18

A pregnancy where the fertilized egg implants in an area other than the uterus is called

Question

The basic building blocks of DNA are called

Question 20

Monosomy of the X chromosome characterized by a short stocky neck, underdeveloped secondary sexual characteristics, and infertility is called

syndrome.

Question 21

A deletion of the short arm of chromosome 5 with a typical cry that resembles a meowing cat characterize

Question 22

A serious psychological disorder characterized by the fear of becoming obese is called

Question 23

Diffusion of gases between capillary beds and tissues is called respiration.

Question 24

The destruction of alveoli by irritants such as cigarette smoke and agricultural dust is found in a disorder called

Question 25

Of the three types of skin cancer which are the most likely to metastasize

Question 25 options:

Melanoma

Squamous cell carcinoma

Basal cell carcinoma

All of the above have equal ability to metastasize

Question 26

Cancer of this organ/gland causes the most deaths annually

Question 26 options:

Lung

Breast

Prostate

Bladder

Question 27

The correct order of stages of the cell cycle that a new cell will go through immediately after being produced by mitosis is

Question 27 options:

S, G1, G2, M

G1, G2, M, S

G1, S, G2, M

M, G1, S, G2

Question 28

What is the purpose of DNA replication

Question 28 options:

To copy the information in a gene so that extra protein synthesis can be done

To make an RNA copy of the gene

To provide the cell with extra DNA in case the original gets damaged

To ensure that two cells produced by mitosis have the same genetic information as the parent cell

Question 29

Which of the following is not a function and/or advantage of mitosis

Question 29 options:

It can repair damaged tissue

Growth takes place through mitosis

It can replace old or damaged cells

All of the above are functions and/or advantages

Question 30

Which stage of the cell cycle occurs just after mitosis

Question 30 options:

Prophase

Save

Question 31 (1.5 points) Question 31 Unsaved

DNA replication is completed by the end of

Question 31 options:

Prophase

S phase

Question 32

Which of the following is NOT true of DNA

Question 32 options:

Generally double stranded

Stores the cell genetic information

Replicated by DNA polymerase

Contains A, C, U, and G

Question 33

These cell may enter G0 of the cell cycle permanently

Question 33 options:

Hepatocytes

Transformed cells

Neurons

Cells in the digestive system

Question 34

When a primary spermatocyte, goes through meiosis, how many mature sperm will be produced

Question 34 options:

Question 35

When a primary oocyte goes through meiosis, how many mature eggs will be produced

Question 35 options:

1)What experiment was performed that allowed for scientists to finally agree that DNA is the genetic material within living organisms?

a.Understand the materials and scientific techniques used to come to this result.

2)What group of experiments led to the discovery of the mechanism used in DNA replication?

a.Understand the materials and scientific techniques used to come to this result.

i.What is a cesium chloride gradient?

ii.Where do 14N and 15N respectively fall along this gradient?

b.The results revealed that DNA replicates using which of the three proposed models?

i. Describe the mechanism of each model.

3)What is the role of the following proteins in DNA replication?

a.Helicase

b.Single strand binding proteins

c.Topoisomerase

d.DNA polymerase III

e.DNA polymerase I

f.Primase

g.Ligase

4)What extra steps are taken to be sure the lagging strand does not shorten each time DNA is replicated?

a.What is the role of telomerase in these âstepsâ?

5)In DNA repair, which enzyme has âproof-readingâ capabilities?

1)Which type of cells within our bodies use mitosis to reproduce?

2)Does mitosis create a cell that is different or the same as the parent cell undergoing division?

3)Describe the DNA found in sister chromatids.

4)Describe the DNA found in homologous chromosomes.

5)What occurs during the following stages of the cell cycle?

a.G₁ Phase

b.S Phase

c.G₂ Phase

d.M Phase

What are the phases of mitosis? What events occur in each phase?

1)Does mitosis separate homologous chromosomes, sister chromatids, or both?

2)What is cytokinesis?

a.Which fibers of the cytoskeleton contract to pinch parent and daughter cells apart from one another in animals?

b.How do microtubules move chromosomes to the two poles of a dividing cell?

3)How are centrioles involved in this process?

a.How do plants form two complete cells during cytokinesis?

4)How do bacterial cells reproduce?

5)The cell cycle is controlled at âcheckpointsâ. What occurs at each of the following checkpoints?

a.G₁ Checkpoint

b.G₂ Checkpoint

c.M Checkpoint

6)How do cyclin and cdk act to control the G2 checkpoint?

7)If presented with the schematic of the M checkpoint, you should be able to explain perturbations to the system as well as if the cell will divide or stall at metaphase.

8)Cancerous cells form when the cell cycle checkpoints do not function correctly and continues to divide even though it is damaged in some way. How does the protein p53 function to keep these cells from dividing?

9)Normal cells follow certain rules of growth that cancerous cells do not follow. What are these rules (provide a short definition for each as well)?

10)What is the difference between a benign tumor and a malignant tumor?

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Biology 2382B Lecture Notes - Lecture 10: Aneuploidy, Wee1, Telophase

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