Biology 2382B Lecture Notes - Lecture 13: Paracellular Transport, Cell Junction, Claudin

• School: Western University
• Department: Biology
• Course: Biology 2382B
• Professor: Robert Cumming

Document Summary

Epithelial cells have an apical surface (towards the outside) and a basal surface (down towards the extracellular matrix) Epithelial cells exhibit the following three characteristics: Epithelial cells will be bound tightly to each other to increase strength. You do not want material to pass in between these cells. Intestine cells, selectively take material from the apical surface and transport it to the basal surface. When you eat foods, amino acids, sugars and lipids are actively transported through the cell. Cell junctions and cell adhesions facilitate the functions of the epithelial cells. Ju(cid:374)(cid:272)tio(cid:374)s pla(cid:455) a (cid:272)ore role i(cid:374) epithelial (cid:272)ells (cid:271)ut the(cid:455) do(cid:374)"t (cid:374)e(cid:272)essaril(cid:455) pro(cid:448)ide strength. In general, gap junctions and tight junctions are not associated with cytoskeletal components. The(cid:455) are asso(cid:272)iated a little (cid:271)it, (cid:271)ut the(cid:455) are(cid:374)"t held i(cid:374) pla(cid:272)e (cid:271)(cid:455) the cytoskeleton. You can easily rip these junction apart. But the (cid:272)ell ju(cid:374)(cid:272)tio(cid:374)"s jo(cid:271) is(cid:374)"t strength. 6 connexin proteins come together on one cell membrane to form a.