Biology 2382B Lecture Notes - Lecture 7: Hoechst Stain, G1 Phase, G2 Phase

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Lecture 7 mitosis and cell cycle control. Learning objectives: cell cycle, mpf and control of g2 m transition, cell cycle regulation. Essential mechanism by which all living things reproduce and pass on genetic information to next generation of cells. Ensures that dna in each chromosome is faithfully replicated to produce 2 copies: replicated chromosomes must be accurately distributed (segregated) into 2 genetically identical daughter cells, coordination of growth (increase in cell mass) with division. The cell cycle and its phases: cell cycle is the ordered sequence of events in which a cell duplicates its chromosomes and divides into two genetically identical cells. Four phases g1, s, g2, & m: g1-s-g2 = interphase, cells don"t look that different, the cell increases in size, m phase = mitosis, most dramatic events observed microscopically, cell divides. Phases of the cell cycle: g1 (gap 1) phase, generalized growth and active metabolism of the cell, variable length (~11 hours in mammalian cells)

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