Class Notes (836,562)
Canada (509,854)
Biology (6,816)
Lecture 5

Cell Bio Lecture 5.docx

1 Page
47 Views
Unlock Document

Department
Biology
Course
Biology 2382B
Professor
Robert Cumming
Semester
Fall

Description
Types of Vesicles- based on coat GTP Binding Protein controls Coat Anterograde Transport – COP11 VESICLES Protein proteins -GTP binding protein to patch of donor membrane COPII-Anterograde Transport -Coat proteins then bind to cytosolic domain of (RERGolgi) membrane cargo proteins (COPII recognizes sorting COPI-Retrograde Transport (CGNRER) signal, DXE) -Recycles membrane bilayer and certain -Coat gives curvature to membrane and acts as filter to Golgi Complex proteins, and mis-sorted RER proteins Retrograde Transport – COP1 VESICLES vesicle from Golgi to ER KDEL Receptord, shed coat proteins revealing v-snare -located mainly in Cis-Golgi Network, and in COPII, COPI -Fuse with Golgi via v-snare and t-snare interactions -Binds proteins bearing KDEL Sorting signal and returns them to RER -cis; nearest the RER -KDEL Receptor has KKXX Sorting signal which binds to -trans; farthest from the RER COPI proteins -Prevents depletion of RER luminal proteins -flattened, disk-like, cisternae with no Binding affinity of KDEL receptor is sensitive to pH ribosomes -Lower pH; high binding affinity (triggers COPI) -Processing and sorting of proteins (secreted, membrane, lyso
More Less

Related notes for Biology 2382B

Log In


OR

Join OneClass

Access over 10 million pages of study
documents for 1.3 million courses.

Sign up

Join to view


OR

By registering, I agree to the Terms and Privacy Policies
Already have an account?
Just a few more details

So we can recommend you notes for your school.

Reset Password

Please enter below the email address you registered with and we will send you a link to reset your password.

Add your courses

Get notes from the top students in your class.


Submit