Biology 2483A Lecture Notes - Lecture 2: Immunology, Meiosis, Signal Transduction

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16 Oct 2017
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Describe the structure and common components of eukaryotic membranes. Membrane is less than 10nm thick selectively permeable. Much larger than lipids - therefore they move slower than lipids. Most proteins move within the membrane, but few anchor cytoskeleton filaments to membrane and do not move. Integral protein: embedded in bilayer interacts with aqueous (interior and exterior of cell) and the core polar outside & inside non-polar core distinct domains of polarity. Peripheral protein surface of membrane no interactions with hydrophobic core. Proportions of lipids and proteins vary depending on the membrane type. Membrane asymmetry: components of each lipid bilayer half are different - each half have different functions. +- proteins and lipids can have carbohydrates attached to them (glycoproteins and glycolipids) Describe how the fluid mosaic model fits what is known about the plasma membrane with respect to membrane structure/characteristics.

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