Biology 2581B Lecture Notes - Lecture 8: Muller'S Morphs, Wild Type, Antennapedia
Document Summary
Based on molecular change: base insertion, deletion etc. Based on effect of translation and on function. Change an a to c: no change because the mutated codon still codes for same amino acid. Wobble position: the last alternating letter of a 3-letter codon that still codes for same amino acid. Typically a mutation in the first or second codon position will change the amino acid: changing non-polar to polar amino acid will have an affect. Nonsense mutation: changing codon to a stop codon, which causes a stop in translation: uaa uag uga are stop codons. If the stop is placed right before the original stop then affects wont be severe. Frame shift mutations: a base is inserted/deleted, which changes every amino acid after that insertion. If 3 bases (or multiple of 3) is inserted, then a full single amino acid is added thus no frameshift. If this occurs near the end not much change will occur in the protein.