Biology 2581B Lecture Notes - Lecture 4: Abo Blood Group System, Heterochromatin, Centromere
7 May 2019
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Document Summary
Abo blood type alleles: scored for blood type appears on surface of red blood cells. Enucleate in mammals-don"t have a nucleus but use to. Those genes were expressed and antigens were inserted onto the surface membrane of red blood cells: able to get blood types base on antigens that appeared on surface, each person has 2 alleles of possible 3. Tissue types: white blood cells (have nuclei) express antigens use for tissue typing hla genes . Hla: appear in a family on chromo 6 (cluster of genes) Each gene has several alleles in the population (why its hard to find tissue match-so much variation) Haplotype: combination of distinct alleles (each person have 2 for hla) Case study-mj: karyotype, blood type is normal, 4 haploid type found in hair, skin, thyroid, blastocyst is multicellular structure, 1,3 fertilizations from mj dad (1) and mom (3) makes zygote. However there is another fertilization from dad (2) and mom (4)
