Biology 1001A Lecture Notes - Lecture 12: Genotype Frequency, Product Rule, Allele Frequency

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In the absence of selection, being recessive or dominant has no effect on the fate of an allele. Probability: product rule in punnet squares, heterozygous individual: half of gametes form one allele and other half form another allele, x = to get recessive alleles. Hardy weinberg equilibrium: can solve for frequencies of each allele. If population is at genetic equilibrium: can predict genotypes from allele frequencies, conditions for hardy weinberg equilibrium, large population, mates randomly, mutation rate= 0 or close, no gene flow, no selection. If conditions are met: there is no evolution, can predict genotype frequencies based on allele frequencies using (p+q)^2, determining equilibrium for a population, provided: observed phenotype/genotype frequencies. If p and q are known, p^2 + 2pq + q^2= 1: compare genotype frequency that was observed to genotype frequency that is expected, null model- hardy weinberg situation. If genotype frequency is (p+q)^2, it is in equilibrium at that locus.

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