Biology 1001A Lecture Notes - Lecture 7: Semiconservative Replication, S Phase, Interphase
4 Dec 2015
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O dna is replicated during s phase (which is a part of interphase) Period when dna replicates and chromosomal proteins are duplicated: g0 cell cycle arrest dividing. Cells just chill in g for most of the time and not actively. Can be reactivated to start dividing: g1 period of growth before the dna replicates. Pairing is always antiparallel: replication is semi-conservative also semi-discontinuous also. Meselson and stahl confirmed this because one new strand and one new strand results: dna polymerase only adds to a free 3 prime end on the. Replisomes replicate one strand continuously, one discontinuously. Oh (hydroxyl: bacterial chromosomes are circular, replication bubble arises from forks created at one origin. Origin of replication: a dna sequence that is recognized by proteins, open up dna and allow replisomes to form. Replisomes form on both sides of origin and one. Dna replication phases goes to left and right. Create structure called replication bubble: replication bubble: is just two forks.
