Biology 1001A Lecture Notes - Lecture 13: Heterozygote Advantage, Allele Frequency, Inbreeding
9 Apr 2016
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Condiion needed for hardy-weinberg: no selecion, no mutaion, no gene low (no geneic drit, large populaion (no immigraion, random maing. Average relaive itness (w) ----> individual itness: measure of itness, total number of surviving ofspring that an individual produces throughout its lifeime (average fecundity) x (proporion survival) Average relaive itness (w) ----> itness of genotypes relaive to other genotypes: w = w/wmax, itest genotype is w=1, selecion strength relects the diference between w values greater w diference = stronger selecion = faster evoluion. Favourable dominant alleles will increase in frequency rapidly but never achieve a frequency of 1 because the recessive alleles are hidden in heterozygote"s. Favourable recessive alleles will increase in frequency slowly and can achieve a frequency of 1 because the dominant alleles can be removed from the gene pool by a selecive pressure. Dominance on its own cannot alter allele frequencies: when paired with selecive pressure you must know the dominance status of the allele.
