Biology 1001A Lecture Notes - Lecture 6: Dna Mismatch Repair, Dna Ligase, Deoxyribonuclease

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Originate from the main bacterial chromosome or from plasmids. Carried along as it moves around: why many antibiotics have lost e ectiveness. The sna copy is inserted in dna at new location, and original stays too. So, they are biological mutagens that increase genetic variability. General trends in costs of dna sequencing: after human genome project, sequencing dna has become possible. As technology improves, the cost of sequencing goes down. After 2007, it has become easier to sequence the genome. Lots of commercial websites will sequence your genome for money and tell you all about your genome (if you carry any recessive, hereditary illnesses, whether you sneeze when looking up at the sun, for example. ) Relative distribution of various components of genome sequence (junk vs. essential dna: only 2% of the genome codes for genes, 10% is essential, 10% is intron (junk, 55% transposons, viruses, dead genes (junk, 25% unknown (likely junk)

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