Biology 1002B Lecture Notes - Lecture 20: Apoptosis, Ecdysone, Base Pair
24 Sep 2016
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If the mirna and mrna pair perfectly, an enzyme in the protein complex cleaves the target mrna where the mirna is bound to it, destroying the mrna and silencing its expression. If they pair imperfectly, the double stranded segment formed between the mirna and the mrna blocks ribosomes from translating the mrna. Role of cyclins and cdk in cell cycle regulation. Cell cycle is controlled directly by complexes of cyclins and a cyclin dependent protein kinase; cdk. A cdk is activated when combined with a cyclin and then adds phosphate groups to target proteins, activating them. The activated proteins trigger the cell to progress to the next cell cycle stage. Each major stage of the cell cycle begins with activation of one or more cyclin: cdk complexes and ends with deactivation of the complexes by breakdown of the cyclins. Four most common types of cancer in canada. Likely factors contributing to cancer incidence in canada.
