Biology 1002B Lecture Notes - Lecture 13: Caesium, Zygote, Mitosis

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So(cid:373)e (cid:373)utage(cid:374)s are tauto(cid:373)eri(cid:272)all(cid:455) u(cid:374)sta(cid:271)le (cid:271)ase (cid:862)a(cid:374)alogues(cid:863: bromouracil dna polymerase cannot distinguish bromouracil from thymine. Radiation is one of the mechanism of mutation most people know of: vast majority of radiation is perfectly natural. You are mostly water, and these radiations go through your water and rip electrons away from oxygen, and water and so the water and oxygen attempt to gain those electrons back and end up pulling electrons from proteins. De(cid:272)a(cid:455) of radioa(cid:272)ti(cid:448)e iodi(cid:374)e a(cid:374)d (cid:272)esiu(cid:373) (cid:272)reates (cid:862)io(cid:374)izi(cid:374)g radiatio(cid:374)(cid:863) Iodine has a relatively shot half-life, cesium has a relatively long one. Burkitt lymphoma: translocation deregulates a cancer gene. Unequal recombination can generate copy number variations (cnv: a) normal crossing-over. Crossing over occurs between homologous chromatids during prophase 1 of meiosis. Normally crossing over occurs at the same exact point on each homolog and results in recombinant chromosomes after meiosis that have the same number of genes in each homolog: b) unequal crossing-over.

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