Biology 1002B Lecture Notes - Lecture 14: Transfer Rna, Chromatin, Nuclear Pore

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Location of eukaryotic gene signals. *the targeting signal is in the coding region. 1: basic structure of eukaryotic vs. prokaryotic cell with respect to gene expression. Eukaryotic cells are compartmentalized- they can keep their ribosomes way from their mrna until the mrna leaves the nucleus. In the nucleus, ribosomes are kept away from the mrna: allows rna processing (posttranscriptional regulation, allows greater control of transcription. Translational and post- translational regulation (alternative splicing) Promoters attract tata binding protein. Far more of the sequence between start and stop is introns for most of your genes. Contains tata box (about 30 base pairs upstream of the transcription start point) Promoters usually have proximal regions upstream of them. Tata binding protein attracts polymerase and several other activators transcription factors that bind onto dna to affect regulation. Promoter is position dependent (must be directly upstream of gene: rna polymerase ii does not bind naked promoters. They have to be bound in the.

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