Biology 1201A Lecture Notes - Lecture 21: Papillary Muscle, Tunica Externa, Elastin

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Layers of a blood vessel: tunica intima the lumen of the blood vessel is surrounded by a layer of endothelial cells. These are the first type of cells that blood will interact with. It"s like the basement membrane but a different composition (still lots of collagen though): on larger vessels, you sometimes find vasa vasorum, tiny blood vessels that supply the tunica externa itself. Tunica externa is then pretty normal (with vasa vasorum and nerve endings: small arterioles also have a normal tunica intima and a large tunica media. Instead of having elastin in the media layer, though, it just has a ton of smooth muscle cell which makes it very strong. Makes sense because arterioles are the vessels that create resistance to change blood pressure. Tunica externa is also pretty normal (with vasa vasorum and nerve endings: capillary unlike the veins and arteries, this is down to the single cell level.

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