Biology 1201A Lecture Notes - Lecture 13: Start Codon, Release Factor, Inosine
15 Jul 2015
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Rna not protein which is doing catalytic action (transferring peptide from 1 site to next) E site: trna; brief before leaves ribosome: trna: short, tiny pieces of rna. Amino acid bound on 3" end & opposite= anticodon- bottom: don"t need 61 trnas b/c of wobble in 3rd base pair. Pairing of 1st & 2nd base of codon=always precise. 3rd base: wobble - > non-standard base pairing; ribosome is not as selective; does not monitor as precisely in that location. 3rd position: g can pair w/ u. Individual identical trnas can bind to multiple codons. Different amino acids can have multiple codons. Codons can be recognized by single trna b/c of wobble: aminoacyl-trna: Specific for an amino acid & for particular trna. Until appropriate trna comes along & binds - > transfers amino acid. Codon- one end, amino acid- other end. Some energy to trna- still maintained in molecule: initiation:
