Biology 1201A Lecture Notes - Lecture 8: Transposase, Hominidae, Copy-Number Variation
8 Nov 2015
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Generating diversity origin of variation 1: new alleles. Reciprocal translocation: when non homologous chromosomes receive pieces of sequence of another non homologous chromosome. Recombination: when homologous chromosomes swap pieces of sequence to another homologous chromosome. ** copy number variation is super prevalent all along chromosomes. Copy number variation: through dna slippage, happens a lot in areas where there are tandem repeats. Some classic diseases that affect humans due to tandem repeat disease: Mobile elements: dna segments that move within the genome. Code for an enzyme called transposase. (can rearrange the sequence or increase the copy number variations. ) Gene families: groups of homologous genes that are likely to have similar functions. (an outcome of a duplication event) *homologous- the same evolutionary origin. (an adjective that can be applied to various things, not just chromosomes)* Picture on last slide- you can see relation from these species, based on similarities and differences in the genes in the gene families.
