Biology 1202B Lecture Notes - Lecture 9: Purine, Polynucleotide, Deoxyribose
21 Feb 2017
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Proteins may perform a variety of other functions in the cell as well. How does the neanderthal ( ~50,000 year old) genome compare to modern humans: single nucleotide polymorphisms (differences, catalogued sites where all (or nearly all) present day humans have the same snp but differ from neanderthal. Differ at 31,389 snps - 87 proteins. The structure of dna: highly stable molecule. Early 1900"s scientists thought protein was the molecule of heredity: 20 amino acids vs 4 nucleotides. Protein contains more information per unit than dna: they took a lot of con(cid:448)incing that it (cid:449)as dna . Despite results of avery and griffith, not all were convinced: protein made sense, scientists had more information about it, they used bacteria - protein & dna, dna does not use sulfur but protein does not. Labelled protein with sulfur and dna with phosphorus: found that when they labelled dna, there was radioactivity in progeny phages. Results (finally) prove dna is the genetic material.
