Biology 1202B Lecture Notes - Lecture 10: Enterobacteria Phage T2, Dna Polymerase I, Semiconservative Replication
Document Summary
The double helix of dna is subject to breakages in one or both strands in addition to inappropriate cross-linking and chemical modification of individual bases. Living cells very successfully prevent or repair most of this dna damage, but post-mortem degradation can be extensive after thousands of years. Nuclein is now known by its modern name, deoxyribonucleic acid, or dna, the molecule that is the genetic material of all living organisms and, as indicated by ancient dna studies, all extinct organisms as well. At the ti(cid:373)e of mies(cid:272)her"s dis(cid:272)o(cid:448)er(cid:455), s(cid:272)ie(cid:374)tists k(cid:374)e(cid:449) (cid:374)othi(cid:374)g a(cid:271)out the (cid:373)ole(cid:272)ular (cid:271)asis of heredity and very little about genetics. Although mendel had already published the results of his genetic experiments with garden peas, the significance of his findings was not widely known or appreciated. It was not known which chemical substance in cells actually carries the instructions for reproducing parental traits in offspring.