Biology 1202B Lecture Notes - Lecture 13: Peripheral Chemoreceptors, Medulla Oblongata, Anaerobic Respiration

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26 Feb 2019
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Mon, Feb. 25/19 Lecture 13: Cellular Respiration III
Understand cellular respiration under these circumstances
Answers in ratios
Oxygen Supply Controls the Fate of Pyruvate
From Glycolysis, pyruvate is produced
Pyruvate can undergo fermentation or pyruvate oxidation
NADH comes from the ETC
NAD+: NADH is low under hypoxic conditions
Lactic acid under hypoxic conditions increases
Aerobic respiration is still occurring when the body is switched into anaerobic respiration
Oxygen Sensors in the Body
Peripheral chemoreceptors detect changes in oxygen levels and send the information to the
medulla oblongata which has central chemoreceptors
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2
The body is always prepared to switch into anaerobic
HIF-1: Transcription factor which activates 60 different genes
Binds to the promoter of genes
Activates pyruvate dehydrogenase kinase which inhibits pyruvate dehydrogenase which
converts pyruvate to acetyl coA
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