Biology 1202B Lecture Notes - Lecture 5: Activation Energy, Enzyme, Catabolism

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All life is made up of monomers and polymers: subunits joined together, nucleic acids, proteins, carbohydrates. Biochemical pathways are involved in synthesizing polymers from monomers: anabolic. Biochemical pathways are involved in breaking down polymers into monomers: catabolic. Many biochemical reactions involve water: h and oh groups added or removed during reaction, removal of water during synthesis (anabolic) reactions, addition of water during breakdown (catabolic) reactions. Chemical reactions involve bond breaking and formation. Bonds must be made less stable in order to break: this requires a small input of energy activation ea, brings reaction to transition state. State at which the reaction will proceed on its own. Even spontaneous reactions may need a small activation energy. Molecules are in constant motion: they may collide in the cytoplasm. Kinetic energy brings reactants to activation state: the motion of those molecules can be increased by increasing the temperature. This can be done in the chemistry lab but not in the cell.

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