Biology 1202B Lecture Notes - Lecture 20: Reverse Transcriptase, Retrovirus, Bacteriophage
28 Mar 2016
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Document Summary
Retroviruses hiv o o o o o o o o o. Review either single stranded or double stranded viruses. Retroviruses are for animal systems nuclear envelopes, all rna viruses diferent from viruses. Reverse transcriptase enzyme that creates cdna in the context of biotechnology applicaions. Some viruses do not put themselves into the integraion of host cell genome, retroviruses always do. The proviral form is the integrated part of dna sequence. Compromises ability to ight virus: no vaccine because they mutate quickly o o. Rapid mutaion which the immune system should recognize causes diiculty (retroviruses are more diicult than viruses) Rna viruses are higher than dna viruses in mutaions. Lifecycle of retroviruses: high mutaion rate from the reverse transcriptase o. In the actual cell you have transcripion of the viral genomes and have a lot of copies of rna or dna sequences similar to each other, causes possibility of dna recombinaion: muliple viruses infecing the same cell o.
