Biology 3436F/G Lecture Notes - Lecture 17: Schizoaffective Disorder, Bipolar Disorder, Schizotypy

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Lecture 17 - nov 28 evolutionary genomics of human brain. We are well adapted to behaviorally navigate a social environment (not just physical one) One approach to understanding the esse(cid:374)(cid:272)e of hu(cid:373)a(cid:374)it(cid:455) is the(cid:396)efo(cid:396)e to stud(cid:455) the (cid:862)so(cid:272)ial (cid:271)(cid:396)ai(cid:374)(cid:863) that is, our capacity for mentalistic cognition. Evolved to deceive, cooperate, get along and avoid conflict, manipulate, lots of social functions that require brain power. I(cid:374)teg(cid:396)ated (cid:374)eu(cid:396)al s(cid:455)ste(cid:373) (cid:858)fo(cid:396)(cid:859) a(cid:272)(cid:395)ui(cid:396)i(cid:374)g a(cid:374)d p(cid:396)o(cid:272)essi(cid:374)g so(cid:272)ial i(cid:374)fo(cid:396)(cid:373)atio(cid:374) Its ultimate function is to predict and otherwise perceive the social dispositions and intentions of others i. e. , an (cid:858)organ of social calculation(cid:859). Evolved in society (social) that promotes having a big brain. Neocortex size is positively correlated with social group size across primates. Plot measure of brain size and social network size positive correlation. Brain size is functionally associated with social function. Consider the evolutionary genetics of two social brain disorders. Relate to functioning of social brain: diametrically opposite to eachother.

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