Chemistry 1027A/B Lecture Notes - Peptide, Protein Family, Random Coil
Document Summary
This is a hypothesis; so it"s not necessarily true. Molecular chaperons are proteins that help with folding. Newly-translated polypeptide (random coil) 3d structure (native state) Various types of motion are possible depending on structure. Often domains can move, connected by flexible linkers. The denatured protein can sometimes return to its original state once the denaturating agent is removed. During evolution, new proteins come from old ones. Protein family: related by evolution (similar but not identical) Amino acid residues that are necessary for function are found in all members.