Health Sciences 3300A/B Lecture Notes - Lecture 19: Seminiferous Tubule, Sertoli Cell, Leydig Cell

• School: Western University
• Department: Health Sciences
• Course: Health Sciences 3300A/B
• Professor: Oleksiy Zaika

Document Summary

Lecture 19 human development: fertilization, implantation, & embryogenesis. These processes are surrounded by sertoli cells until they reach the lumen: spermiogenesis, maturation into spermatozoa. Lumen of the seminiferous tubules: promotion, leydig cells release androgens and secrete testosterone, androgens promote this entire process. Testosterone promotes libido and sex characteristics, and development of mature spermatozoa: testosterone promotes libido and sex characteristics. Sperm: head, nucleus contains genetic data, acrosomal cap with enzymes, enzymes help penetrate barriers that sperm encounters at ovum, breaks down some mucus to get through ovum and some of its protective layers. Tail: neck with centrioles to span tail, mitochondria for energy (middle, creates atp for motility of sperm, principle piece contains centrioles. Initiation: germ cells present in fetus before baby is born, degenerate steadily after birth, competing with each other to get a proper fully-fledged ovum, primary oocyte arrested until puberty. 200k at birth, 40k at puberty, 400 reach maturity in life: protected by granulosa cells, meiosis.