Kinesiology 4430F/G Lecture Notes - Lecture 3: P70-S6 Kinase 1, Insulin, Endurance Training

• School: Western University
• Department: Kinesiology
• Course: Kinesiology 4430F/G
• Professor: Charles Rice

Document Summary

Average person has 12kg of protein in their body -16% Free aa pool 250g of protein can be derived from essential or non- essential aa"s: free aa"s can move freely between blood and muscle cell. Proteins in cells are constantly broken down and resynthesized. Protein turnover 20% of resting basal metabolic rate. Muscle protein turnover is affected by activity, nutrients and hormones. Looking at a labelled essential aa as its synthesized and broke down: resting white, after exercise black. Protein synthesis increases sig. after exercise greater then breakdown increase. Reasonable because you are trying to remodel muscle that you"re using. Net almost have a protein balance: why is it a negative net balance, breakdown is higher than synthesis, they are in a fasted state. From rest to after exercise: there is a less negative net balance increased synthesis more than breakdown after exercise. If breakdown exceeds synthesis, you get a net (-) balance.