Kinesiology 4430F/G Lecture 1: 1 ATP Synthesis in Muscle

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Type 2 2a and 2x, 2b no 2b in humans, seen in animal studies: a + x transitional muscle fibers, highly glycolytic range. Type 1 range of oxidative properties: because they contract more slowly contraction force is less intense than type 2, therefore more energy efficient, metabolic cost is lower. Muscle plasticity: skeletal muscle is remarkably plastic and will respond to the type of load placed upon it, external cues (load) can alter muscle phenotype (ex. how oxidative, how much mitochondria) Sci not activating muscles at all/or very little very small % of type 1 fibres and large % of transitional fibres. Marathon runner primarily type 1 fibers as training increases, you get less and less transitional fibres: becoming more oxidative as you train. Goal of the cell is to maintain atp homeostasis: uses oxidative phosphorylation, high energy phosphate transfer and glycolysis.

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