Kinesiology 2222A/B Lecture Notes - Lecture 4: Keratinocyte, Melanin, Integumentary System

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Differences in skin often comes down to one pigment, how much you have of it, and enzymes related to the pigment. Made up mostly of many many epithelial cells. Keratinized squamous epithelium: keratinized because the main part of epithelial cells is protein, squamous - scale like. The majority of cells in the epidermis are these cells: melanin protects the nuclei of keratinocytes from harmful uv rays. Some merkel cells located here as well: attached to at the epidermis, seen on the bottom layer. Move through the dermis on the pathway back to the cns. Langerhans cells (macrophages: part of the immune system, destroys harmful bacteria. Basale (deep) (think basement: most activity occurs here, lots of replication of cells, furthest away from the external environment, everything above this is somewhat protective of this layer. Spinosum (spider: langerhans present here, term spider comes from the fact that the cells in this layer look spider like when dehydrated.

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