Kinesiology 3339A/B Lecture Notes - Lecture 11: Oxidative Phosphorylation, Mitochondrial Matrix, Saturated Fat

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27 Sep 2018

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Krebs/tch cycle occurs in inner membrane of mitochondria: oxygen required. Glycogen storage in sarcoplasm can be used to produce pyruvate which can be transported into the mitochondrial matrix. All the macronutrients have cross roads to acetyl-coa: aas, fatty acids and pyruvate, acetyl-coa is in the mitochondria and pyruvate is not. H enzymes that are reduced move into the etc and atp is produced. Oxygen is the acceptor of the elector and with the h ions it turns into water. Glycogen storage in muscle has nothing to do with the glucose level in plasma does not contribute to maintenance of blood level: muscle is selfish, glucose in blood comes from diet. In the muscle we don"t have glucose-6-phospotase enzyme so when glucose becomes glucose-6-phosphate, it has to be removed thus it can"t release glucose into the blood. Total atp per glucose breakdown in different pathways:

Related Questions

16. Muscle glycogen cannot contribute directly to blood glucose levels because:

A. Muscle glycogen cannot be converted to glucose-6-phosphate

B. Muscle lacks glucose-6-phosphatase

C. Muscle contains no glycogen phosphoyrlase

D. Muscle lacks phophoglucoisomerase

_____17. Which of one of the following tissues requires insulin for glucose transport into the cell?

A. Brain

B. Liver

C. Skeletal muscle

D. Red blood cells

_____18. The mobilization of triaclyglycerol-bound fatty acids from adipose tissue and their subsequent oxidation by muscle mitochondria require all of the following compounds except:

A. Serum albumin

B. Carnitine

C. Acetyl CoA carboxylase

D. Hormone sensitive lipase

_____19. Which one of the following reactions is unique to gluconeogenesis?

A. Lactate Â® pyruvate

B. PhosphoenolpyruvateÂ® pyruvate

C. OxalacetateÂ® Phosphoenolpyruvate

D. 1,3bisphosphoglycerate Â® 3-phosphoglycerate

_______20. A newborn vomits after each feeding of milk-based formula and doesnât gain weight. Biochemical testing reveals a sever deficiency of galactose-1-phosphate uridyltransferase. If this condition goes untreated, which of the following is the likely outcome for this patient?

A. Benign disease except for cataract formation

B. Chronic emphysema appearing in early adulthood

C. Chronic renal failure appearing in adolescence

D. Death in infancy

E. Gastrointestinal symptoms that remit with puberty

1) The complete catabolism of glucose results in the generation of ___________ ATP.

	1.	29
	2.	100
	3.	20
	4.	50

2) The presence of _____________________ is a determinant factor on whether pyruvate continues its metabolism into the Krebs cycle.

3) As humans we breath in air that contains oxygen and breath out carbon dioxide . The oxygen we consume it is used in the metabolism of glucose in the ________________________.

electron transport chain as an acceptor of electrons

anaerobic respiration

citric acid cycle

4.conversion of pyruvate to acetyl-CoA

4) A glucose molecule can generate energy, but only if sufficient amount of energy is invested to initiate the chemical reactions that are involved in the catabolism of the glucose molecule.

True

False

5) The ___________________ of glycogen from individual/separate molecults of glucose is an ___________________ reaction.

	1.	breakdown, endergonic
	2.	breakdown, exergonic
	3.	synthesis, endergonic
	4.	synthesis, exergonic

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Kinesiology 3339A/B Lecture Notes - Lecture 11: Oxidative Phosphorylation, Mitochondrial Matrix, Saturated Fat

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