Kinesiology 4432A/B Lecture Notes - Lecture 2: Purinergic Receptor, Adenylyl Cyclase, Hemoglobin

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Exercise blood flow: vasodilation & cardiac output: what is more important during exercise: control of blood pressure or blood flow, *total perfusion of exercising skeletal muscle is the most important determinant of exercise capacity. Vo2: oxygen consumption: o2 concentration= blood flow x (arterial o2 content = venous o2 content, vo2= q x (ao2-vo2, vo2=q x (a-v) x o2 where (a-v) x o2 is arteriovenous oxygen difference. A-v is the difference in oxygen content from the arterial to the venous side. Q/co is the most important variable in determining vo2. The ? in the diagram is vo2 max. Trained individuals have higher vo2 max than untrained individuals. 2: the pattern of blood flow to muscle during exercise, redistribution, rapid, ascending vasodilation (addressed later) Blood flow response to the exercising muscle is very fast (local changes are occurring even. Before co has had the chance to change vc outstrips co.

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