Kinesiology 4474A/B Lecture Notes - Lecture 5: Cohort Study, Relative Risk, Vascular Smooth Muscle
6 Mar 2018
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Document Summary
Our ancestors ate large amounts of potassium (150-190 mmol/day) and very small amounts of sodium (1-10 mmol/day), they ate a lot more fish, fruits and veggies. Therefore we have evolved to have powerful excretion mechanisms for potassium and conserving mechanisms for sodium. Now: potassium intake (in most developed countries) has dropped substantially (70 mmol/day) and sodium intake has increased (170-200 mmol/day) = reversal in k and na. Why: reduced potassium intake and increased sodium intake with modern processed foods, reduced consumption of fruits and veggies excellent source of potassium. Effects of high k and low na: increased bp related to low k as much as high na, increased cvd, increased renal disease, increased bone loss. There is an inverse relationship between potassium intake and hypertension. With low k, your vessels become more rigid. This makes the systolic pressure much higher during ejection of the blood from the heart; they don"t expand like they should.
