Microbiology and Immunology 2500A/B Lecture Notes - Lecture 5: African Meningitis Belt, Listeriosis, Pneumococcal Vaccine

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Bacterial meningitis: meninges the membranes that envelop the central nervous system (brain and spinal cord) includes the pia mater, arachnoid mater and dura mater cerebral spinal fluid is between the arachnoid and pia maters. Csf between the layers, acts like a cushion an infection of the meninges. Viral meningitis will work itself out viral meningitis is generally less severe and usually resolves without specific treatment. Bacterial meningitis is extremely dangerous and life threatening. The blood brain barrier (bbb) a protective cellular structure that restricts passage of chemicals, toxins, and microorganisms from the blood to the central nervous system (cns) also protects your cns from the peripheral immune system. Lines epithelial cells and prevents things from moving in and out. Blue stain test: barrier that separates the brain from the rest of the body, it would not stain blue while the other organs would: microglia are the tissue macrophages of the cns.

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