Microbiology and Immunology 2500A/B Lecture 5: Immunology 5
30 Jun 2016
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Document Summary
Polarization of nk contents, resides closer to infected cells. When infected cells die, intracellular cell will also be destroyed via apoptosis represents height of immune response or virus titer. Green, blue, and red curves are components of immune defense system. They increase at different time points following viral infection. Yellow curve represents virus titer which gradually decreases and is lower than the height of the immune response. Following a virus infection, infected cells produce ifn-alpha and beta. Cytokines and interferons appear first which activates nk cells to contain the virus nk cells provide early response to virus. Virus elimination accomplished when virus-specific t cells produced (red) later in course. Cytokine binds to cytokine receptor on another cell or on its own surface. Activates cell to send signal telling it what to do. Haematopoiesis where pluripotent stem cell can become either lymphoid stem cell or myeloid stem cell.
