Microbiology and Immunology 3300B Lecture Notes - Lecture 1: Thiomersal, Formaldehyde, Polio Vaccine
9 Dec 2016
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Document Summary
Who are healthy die from the flu but we vaccinate all of us. Must be safe death much fewer people dying young in the 21st century than the 20th century. Mmr measles, mump and rubella all vaccinated together. Vaccines are strange because you don"t treat people who are sick, you treat people. We also are often not immunizing the people who will benefit most most elderly. Effectiveness: won"t work in everybody, but has to work on enough that we have (cid:498)herd immunity(cid:499) remove humans as a pathogen environment. Live pathogen but attenuated, meaning it"s not as dangerous as one that makes sick. Culture and grow pathogen in non-ideal conditions viruses are trophic for humans, Bacteria use closely related bacteria that infects other species that creates a cross- reactive immune response bcg mycobacterium bovis tuberculosis. Designer attenuation delete or mutate specific and multiple virulence genes.
