Microbiology and Immunology 3820A Lecture 5: Lecture 5 Colby 2017 - Mycobacteria
18 Dec 2017
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Document Summary
Intracellular: they live inside our cells very difficult to get rid of them. Tuberculosis: 1/3 of the world"s population infected, ~30 million active cases. If the sputum stains negative for afb patient is noninfectious. Incidence of tb is low in north america except in first nations, inuit, refugees, Aids and the homeless transmit within short distance): tb was almost eradicated in canada in 1990s. Then the funding was cut instead of triple funding to eradicate b/c the last few cases are harder to eradicate. Then a new class of susceptible host (people with hiv) got infected with tb. Mantoux test: intradermal injection of 5 tuberculin units of ppd: ppd = purified protein derivatives, a bleb will form. Ecg on healthy high school students: increased qt wave but likely not having a mi, false positives outnumber true numbers, ex. Tb rx: recently multidrug resistant strains have appeared, directly observed therapy, specialist consultation essential.
