Pathology 2420A Lecture Notes - Lecture 3: Cell Adhesion Molecule, Vasodilation, Capillary
Document Summary
Explain the vascular events that take place in the capillary bed during an acute inflammatory process. Described abnormal permeability at the microcirculation during acute inflammation (in contrast to normal). Define chemotaxis and list three common chemotactic factors. List the three most common cells involved in inflammation and their role in the inflammatory response. List and explain the mechanism of production of the cardinal signs of inflammation. List at least two systemic effects of inflammation. A nonspecific, dynamic response of living cells to tissue injury. Results from non-lethal: physical trauma, chemical injury, infection with a microorganism, immune reactions. Non specific- inflammation will always be the same regardless of injury. Inflammation acts to limit the spread of the injurious agent and allow for repair/replacement of damaged tissue. Main players: vessels (vascular events, cells (cellular events, chemical mediators- can act on vessels or cells.