Philosophy 2715F/G Lecture 13: week 7

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Transfer of authority over a significant practical interest, such as medical, legal or financial interests. Duty to act and advise so as to promote the medical interest of the patient: standard of care as a specification of the duty. Treatment endorsed by at least a respectable minority of expert practitioners. Clinical research: question: how can the conduct of clinical research be consistent with the duty of care, translational trajectory of clinical research, potential drug of use is identified: Laboratory or modeling: testing in animal models: Efficacy (if an animal model esists: phase 1 trials: Randomized controlled trial: patients with a disease, randomized to 2 treatments, baseline and outcome data. If the physician has a duty of care to the patient, how can allocating treatment randomly be consistent with this duty: equipoise: Genuine uncertainty regrading the comparative merits of the two treatments: but how should we understand this notion, theoretical equipoise:

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